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It is possible that the cysteinyl axial ligand in cytochrome P-450 plays an important role in OO bond cleavage, and that the interactions found in catalase and peroxidase that appear to facilitate such cleavage are therefore not necessary.

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References: Katona et al (1977)

Caponio VCA, Troiano G, Adipietro I, Zhurakivska K, Arena C, Mangieri D

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